Infatuation Rules
Photo: Letticia Massari
In the past, other scientists have suggested that dad's genes are more robust because men need their children to look like them in order to believe they're really the baby's father. That makes intuitive evolutionary sense, given that men can't be certain about their children's parentage the way women are.
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Read More »When a baby is born, three cliché things are done immediately: announcing its gender to the world; counting the kiddo’s fingers and toes; and, inevitably, deciding which parts of its red, angry alien body look like mom and which look like dad. That last conversation actually never really stops, with quips like “your eyes are just like your mother’s!” and “your nose is just like your father’s!” plaguing every family reunion. Well, next time you want to distract from this family pasttime, drop some science on your relatives and let them know that, genetically speaking, we’re all a lot more like our fathers.
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Read More »But even that empirically grounded explanation has its limits, Chuong notes. One classic example of this genetic conflict is seen in the fight for expression of insulin-like growth factor 1, or IGF protein. This protein, which promotes growth, is strongly expressed by paternal genes. Maternal genes, meanwhile, express something called IGF2R, which actively suppresses the father’s IGF protein production and, therefore, the baby’s growth. “In mice, if you knock out the maternal genes, the babies become giant,” Chuong says. They try to outgrow their siblings and extract more and more resources from their mother. Conversely, Chuong says, if you knock out a father’s genes, the babies become small — too small, actually. Turns out, the mother’s growth-suppressing genes weren’t always there. They only developed in response to the dad’s growth-promoting genes. “It’s like a tug of war,” he says. “These almost cancel each other out.” Without the father’s growth-promoting genes to battle against, a mother’s inhibiting genes can actually hurt the babies. In natural environments, where both the mother and father are contributing the right stuff, offspring come out at optimal sizes. In the past, other scientists have suggested that dad’s genes are more robust because men need their children to look like them in order to believe they’re really the baby’s father. That makes intuitive evolutionary sense, given that men can’t be certain about their children’s parentage the way women are. But the evidence is actually all over the place, with just as many studies suggesting babies look more like their moms. While the mysteries of the genome — and the epigenome — have yet to be unraveled, one thing’s clear: Dad’s are pretty important.
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