Infatuation Rules
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What is the strongest type of bond in biology?

Covalent bonds are the strongest bonds in nature and under normal biological conditions have to be broken with the help of enzymes. This is due to the even sharing of electrons between the bonded atoms and as with anything equally shared there is no conflict to weaken the arrangement.

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Attractive Forces

Covalent bonds involve the equal sharing of an electron pair by two atoms. Examples of important covalent bonds are peptide (amide) and disulfide bonds between amino acids, and C-C, C-O, and C-N bonds within amino acids. Coordinate covalent bonds involve the unequal sharing of an electron pair by two atoms, with both electrons (originally) coming from the same atom. The electron pair donor is the ligand, or Lewis base, whereas the acceptor is the central atom (because it frequently can accept more than one pair of electrons), or Lewis acid. These bonds are important in all interactions between transition metals and organic ligands (e.g., Fe2+ in hemoglobin and the cytochromes). Ionic interactions arise from electrostatic attraction between two groups of opposite charge. These bonds are formed between positively charged (α-ammonium, ε-ammonium, guanidinium, and imidazolium) side chains and negatively charged (ionized forms of α-carboxyl, β-carboxyl, γ-carboxyl, phosphate, and sulfate) groups. Hydrogen bonds involve the sharing of a hydrogen atom between two electronegative atoms that have unbonded electrons. These bonds, although weak compared to the bonds discussed above, are important in water-water interactions and their existence explains many of the unusual properties of water and ice (Chapter 1). In proteins, groups possessing a hydrogen atom that can be shared include N-H (peptide nitrogen, imidazole, and indole), -SH (cysteine), -OH (serine, threonine, tyrosine, and hydroxyproline), -NH 2 and − NH 3 + (arginine, lysine, and α-amino), and -CONH 2 (carbamino, asparagine, and glutamine). Groups capable of sharing a hydrogen atom include -COO- (aspartate, glutamate, and α-carboxylate), -S-CH 3 (methionine), -S-S- (disulfide), and (in peptide and ester linkages). Van der Waals attractive forces are due to a fixed dipole in one molecule that induces rapidly oscillating dipoles in another molecule through distortion of the electron cloud. The positive end of a fixed dipole will pull an electron cloud toward it; the negative end will push it away. The strength of these interactions is strongly dependent on distance, varying as 1/r6 where r is the interatomic separation. The Van der Waals forces are particularly important in the nonpolar interior structure of proteins, where they provide attractive forces between nonpolar side chains. Hydrophobic interactions cause nonpolar side chains (aromatic rings and hydrocarbon groups) to cling together in polar solvents, especially water. These interactions do not produce true “bonds,” since there is no sharing of electrons between the groups involved. The groups are pushed together by their “expulsion” from the polar medium. Such forces are also important in lipid-lipid interactions in membranes.

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What's the best age to get into a serious relationship?

It's important to consider your child as an individual. Consider their emotional maturity and sense of responsibility. For many kids, 16 seems to be an appropriate age, but it may be entirely suitable for a mature 15-year-old to go on a date, or to make your immature 16-year-old wait a year or two.

When your child mentions dating, or a girlfriend or boyfriend, try to get an idea of what those concepts mean to them. Take note of how your child reacts when you discuss dating. It could be a little uncomfortable or embarrassing, but if your child is unable to even discuss it with you without getting defensive or upset, take that as a sign that they probably aren’t ready.

Other things to consider include the following.

Is your child really interested in someone in particular, or are they just trying to keep up with what friends are doing?

Do you think your son or daughter would tell you if something went wrong?

Is your child generally confident and happy?

Does your child’s physical development match their emotional development?

Be aware that for many tweens and young teenagers, dating amounts to socializing in a group. While there may be interest between two in particular, it’s not double-dating so much as a group heading out or meeting up at the movies or the mall. This kind of group stuff is a safe and healthy way to interact with members of the opposite sex without the awkwardness that a one-on-one scenario can bring. Think of it as dating with training wheels. So, when is a child ready for one-on-one dating? There’s no right answer. It’s important to consider your child as an individual. Consider their emotional maturity and sense of responsibility. For many kids, 16 seems to be an appropriate age, but it may be entirely suitable for a mature 15-year-old to go on a date, or to make your immature 16-year-old wait a year or two.

You can also consider what other parents are doing. Are lots of kids the same as yours already dating in the true sense of the word?

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