Infatuation Rules
Photo: Pavel Danilyuk
Oxytocin, also known as the love or bonding hormone, promotes feelings of intimacy and closeness. The body releases it after orgasm.
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Read More »Oxytocin is a hormone and a neurotransmitter that is involved in childbirth and breast-feeding. It is also associated with empathy, trust, sexual activity, and relationship-building. It is sometimes referred to as the “love hormone,” because levels of oxytocin increase during hugging and orgasm. It may also have benefits as a treatment for a number of conditions, including depression, anxiety, and intestinal problems. Oxytocin is produced in the hypothalamus, a part of the brain. Females usually have higher levels than males. Fast facts on oxytocin Oxytocin is produced in the hypothalamus and released during sex, childbirth, and lactation to aid reproductive functions.
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Read More »Oxytocin and emotion When oxytocin enters the bloodstream, it affects the uterus and lactation, but when it is released into certain parts of the brain, it can impact emotional, cognitive, and social behaviors. One review of research into oxytocin states that the hormone’s impact on “pro-social behaviors” and emotional responses contributes to relaxation, trust, and psychological stability. Brain oxytocin also appears to reduce stress responses, including anxiety. These effects have been seen in a number of species. The hormone has been described as “an important component of a complex neurochemical system that allows the body to adapt to highly emotive situations.” Is it that simple? In 2006, investigators reported finding higher levels of oxytocin and cortisol among women who had “gaps in their social relationships” and more negative relations with their primary partner. The participants were all receiving hormone therapy (HT) following menopause. Animal studies have found high levels of both stress and oxytocin in voles that were separated from other voles. However, when the voles were given doses of oxytocin, their levels of anxiety, cardiac stress, and depression fell, suggesting that stress increases internal production of the hormone, while externally supplied doses can help reduce stress. Clearly, the action of oxytocin is not straightforward. A review published in 2013 cautions that oxytocin is likely to have general rather than specific effects, and that oxytocin alone is unlikely to affect “complex, high-order mental processes that are specific to social cognition.” The authors also point out that a willingness to collaborate is likely to be driven by anxiety in the first place. Nevertheless, oxytocin does appear to be associated with social behavior, including maternal care, bonding between couples, sexual behavior, social memory, and trust. Behavioral effects Delivering oxytocin through a nasal spray has allowed researchers to observe its effects on behavior. In 2011, research published in Psychopharmacology found that intranasal oxytocin improved self-perception in social situations and increased personality traits such as warmth, trust, altruism, and openness. In 2013, a study published in PNAS suggested that oxytocin may help keep men faithful to their partners, by activating the reward centers in the brain. In 2014, researchers published findings in the journal Emotion suggesting that people saw facial expression of emotions in others more intensely after receiving oxytocin through a nasal spray.
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Read More »Psychiatric therapy Oxytocin has been proposed as a possible treatment for social phobia, autism, and postpartum depression. Scientists have proposed that it might help improve interpersonal and individual wellbeing, and that it could have applications for people with some neuropsychiatric disorders. They believe it could help people who avoid social interaction, and those who experience persistent fear and an inability to trust others. Children with autism could benefit from oxytocin, say some researchers. In 2013, a small study suggested that oxytocin levels in the brain affected how 17 children perceived a series of social and non-social images. Oxytocin may also play a role in anger management. Research has indicated that certain polymorphisms of the oxytocin receptor (OXTR) gene are associated with an increased tendency to react angrily to situations. In particular, differences in OXTR gene expression appear to affect the regulation of the relationship between alcohol and aggressive behavior. Uses Oxytocin appears to increase the release of prostaglandin E2 (PGE2) in cells lining the intestine. This helps to encourage the repair of intestinal injury and to protect against such injury. If this is confirmed, oxytocin could be a useful therapy for preventing chemo-radiotherapy-induced intestine injury, and it could be used to treat irritable bowel syndrome (IBS).
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